| Lysis vs lysogeny decision in the phage lambda |
Phage Lambda |
Lysis-lysogeny decision |
| Gap Model |
D. melanogaster |
Segmentation, Development |
| The pair-rule cross-regulatory module |
D. melanogaster |
Segmentation, Development |
| Controlling tryptophan biosynthesis |
E. Coli, Bacterium |
Tryptophan biosythesis |
| DV boundary formation of the Wing imaginal disc |
D. melanogaster |
Wing Imaginal disk, Development |
| Restriction point control of the mammalian cell cycle |
Mammal |
Cell cycle |
| TCR signalisation |
Mammal |
Differentiation |
| Control of Th1/Th2 cell differentiation |
Mammal |
Differentiation |
| Budding yeast cell cycle (Orlando et al. 2008) |
Yeast, Budding yeast |
Cell cycle |
| The Anterior-Posterior Boundary (Gonzalez et al. 2008) |
D. melanogaster |
Wing Imaginal disk, Development |
| Segment polarity module (Sánchez et al. 2008) |
D. melanogaster |
Segmentation, Development |
| Fission Yeast Cell Cycle (Davidich and Bornholdt, 2008) |
Yeast, Fission yeast |
Cell cycle |
| Network model of survival signaling in large granular lymphocyte leukemia (Zhang et al 2008) |
Mammal, Blood cells, T lymphocytes |
Cell fate decision |
| Budding yeast cell cycle (adapted from Irons, 2009) |
Yeast, Budding yeast |
Cell cycle |
| Core engine controlling the budding yeast cell cycle |
Yeast, Budding yeast |
Cell cycle, Core engine |
| Budding yeast cell cycle (Fauré et al. 2009) |
Yeast, Budding yeast |
Cell cycle |
| Budding yeast exit module |
Yeast, Budding yeast |
Mitosis exit control, Cell cycle |
| Morphogenetic checkpoint of the budding yeast cell cycle |
Yeast, Budding yeast |
Cell cycle, Morphogenetic checkpoint |
| ERBB receptor-regulated G1/S transition |
Human |
Cell cycle |
| p53-Mdm2 network involved in DNA repair |
Mammal |
Cancer, DNA repair |
| Cell-Fate Decision in Response to Death Receptor Engagement |
Mammal |
Cell fate decision |
| Control of Th1/Th2/Th17/Treg cells differentiation |
Mammal |
Differentiation |
| Drosophila cell cycle |
D. melanogaster |
Cell cycle |
| miR-9 and timing of neurogenesis (Coolen 2012) |
Zebrafish |
Development, Differentiation |
| Specification of vulval precursor cells and cell fusion control in C. elegans |
C. elegans |
Differentiation |
| Drosophila FGF Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila JAK/STAT Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila Dpp Signalling pathway |
D. melanogaster |
Wing Imaginal disk, Development, Signalling |
| Drosophila EGF Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila Hh Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila Notch Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila SPATZLE Processing pathway |
D. melanogaster |
Signalling |
| Drosophila Toll Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila VEGF Signalling pathway |
D. melanogaster |
Signalling |
| Drosophila Wg Signalling pathway |
D. melanogaster |
Signalling |
| MAPK network |
Mammal |
Signalling |
| Drosophila eggshell patterning |
D. melanogaster |
Development |
| Mast cell activation |
Mammal, Blood cells |
Signalling |
| Senescence onset at the G1/S cell cycle checkpoint |
Mammal |
Senescence, Cell cycle, Cell fate decision |
| Control of Th1/Th2/Th17/Treg/Tfh/Th9/Th22 cell differentiation |
Mammal, Blood cells, T lymphocytes |
Differentiation |
| Mutually exclusive and co-occurring genetic alterations in bladder tumorigenesis |
Mammal, Human |
Cancer, Signalling, Cell fate decision |
| Cell fate decision network in the AGS gastric cancer cell line (Flobak et al 2015) |
Mammal |
Cancer |
| Molecular Pathways Enabling Tumour Cell Invasion and Migration |
Mammal, Human |
Cancer, Signalling |
| Logical modelling of myelofibrotic microenvironment predicts dysregulated progenitor stem cell crosstalk |
Mammal, Stem cells, Haematopoietic stem cells, Mesenchymal stem cells |
Cell fate decision |
| Drosophila mesoderm specification |
D. melanogaster |
Development, Signalling |
| Multilevel mammalian cell cycle model |
Mammal |
Cell cycle |
| Boolean model of geroconversion |
Mammal |
Senescence |
| Communication pathways between Hematopoietic Stem Progenitor Cells (HSPCs) and Mesenchymal Stromal Cells (MSCs) |
Mammal, Blood cells |
Cell fate decision |
| Primary sex determination of placental mammals |
Mammal |
Development, Sex determination |
| Asymmetric Cell Division in Caulobacter Crescentus |
C. Crescentus, Bacterium |
Asymmetric cell division, Cell cycle |
| Lymphoid and myeloid cell specification and transdifferentiation |
Mammal, Blood cells |
Differentiation |
| Primary sex determination of chicken gonads |
Mammal, Bird |
Development, Sex determination |
| TCR and TLR5 merged Boolean model |
Mammal |
T-cell activation |
| Comprehensive Boolean model of the mammalian cell cyle control network |
Mammal, Human |
Cell cycle, Signalling |
| Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation |
Mammal, Human |
T-cell activation |
| T-lymphocyte specification |
Mammal |
Differentiation, Signalling, Development |
| Regulation of p21-dependent senescence-apoptosis switch by the ATM/miR-34a-5p axis in non-small cell lung cancer |
Mammal |
DNA repair, Cell cycle |
| Differential expression of IL17 isoforms A and F in helper T Lymphocytes |
Mammal |
differentiation |
| Microenvironment control of hybrid Epithelial-Mesenchymal phenotypes |
Mammal |
Cancer |
| Immune checkpoints |
Mammal, Human |
T-cell activation |
| Immunogenic Cell Death |
Mammal |
Cancer |
| Control of proliferation by oncogenes and tumor suppressors |
Mammal |
Cancer |
| T cells response to CTLA4 and PD-1 checkpoint inhibitors |
Mammal |
Differentiation |
| Logical model of the regulatory network controlling dorsal-ventral axis specification in the sea urchin P. lividius |
Sea Urchin |
Development |
| Response to BRAF treatment in melanoma and colorectal cancer |
Mammal, Human |
Cancer |
| Differentiation of Monocytes to Dendritic Cells |
Mammal, Human |
Differentiation |
| Signalling in prostate cancer |
Mammal, Human |
Cancer |
| Logical model of the regulatory network underlying Retinoic Acid resistance in Acute Promyelocytic Leukaemia |
Mammal |
Cancer |